Article published by : Sumit Choudhari on Thursday, July 25, 2019 - Viewed 319 times


Category : Health & Fitness

Global Orphan Drugs Market by Type and Size | Industry Report 2018-2023

Global Orphan Drugs Market - Synopsis

Orphan drugs are generally used for treating rare disorders and diseases that affect a small percentage of the population. There are approximately 30 million in Europe, 30 million people in the US, and 350 million people worldwide who suffer from 7,000 types of rare diseases.

Disorders among which four-fifths of the rare diseases are genetic and 50 % of the crowd affected being children. Only 5 % of the rare diseases had approved drug treatment with 326 new drugs being approved by FDA and brought to the market.

Competition Analysis:

The key players operating the orphan drugs market are

Alexion Pharmaceuticals Inc.
Bayer AG
Celgene Corporation
Novartis AG
Biogen Idec Limited
Hoffmann- La Roche
Takeda Pharmaceuticals Company Limited
Bristol-Myers Squibb
Vertex Pharmaceuticals Inc.
Johnson & Johnson
Segmentation Analysis:

Globally, the market for orphan drugs has been segmented on the basis of application, pharmacological class, source, technology, and region.

The market has been segmented into enzyme replacement, protein replacement, and gene chromosome expression based on pharmacological class.

The market has been segmented into oncology, blood-related disorders, neurology, nephrology, and infectious diseases based on applications. Among these, oncology is predicted to dominate the market owing to the increasing drug approvals for treating rare cancers.

The market has been segmented into Transgenic, DNA recombination, and gene expression based on technology.

The market has also been segmented into biological orphan drug and non-biological orphan drug based on source. Among these, biological orphan drug leads the market in terms of revenue and is predicted to maintain its dominance over the assessment period owing to the high efficacy of biologic products for treating diseases.

Future Drivers and Constraints Affecting the Market

Growing investment in R&D, unmet requirement for rare diseases, economic, legislative, and tax benefits offered by the government, high ROI, development of latest technologies like hybridoma, gene mapping, and DNA recombinant, extensive exclusivity, and faster uptake and low marketing cost are some of the major factors driving the market over the forecast period.

There has been a growing demand for drugs for rare diseases such as Yellow Fever, Von Willebrand Disease, Aarskog Syndrome, Waardenburg Syndrome, diabetic macular edema, Abetalipoproteinemia, Autism spectrum disorder (ASD), Yellow Nail syndrome, Asperger syndrome, Von Hippel-Lindau Disease, and others which is contributing towards the growth of the market. Moreover, FDA free waivers, R&D grants by the government, favorable reimbursement policy along with premium pricing owing to the low competition also contribute the market growth.

Meanwhile, high cost of development, extensive post-market surveillance, costly clinical trials, monopolized and unitary market, concern over safety, competition from biosimilars and generics are some of the restraining factors inhibiting the growth of the market over the forecast period. Moreover, active distribution and commercialization can be hindered by differential availability of developing and developed countries, owing to socio-economic factors.

Global Orphan Drugs Market - Industry News

The FDA has granted orphan drug designation to Surface Oncology's lead investigational candidate SRF231 which is a potential treatment for patients suffering from multiple myeloma. The SRF231 is a human monoclonal antibody therapeutic targeting CD47, a protein overexpressed on cancer cells to prevent them from being eliminated and engulfed by macrophage-mediated phagocytosis.

Browse Complete 84 Pages Premium Research Report Enabled with 121 Respective Tables and Figures @

North America to Dominate the Market

Geographically, the market for orphan drugs has been spanned across regions such as North America, Europe, Asia Pacific, Middle East and Africa.

North America has been estimated to hold the largest market share owing to well-established healthcare infrastructure, favorable regulations for drug approval for rare diseases, initiatives by non-governmental and governmental agencies to increase awareness related to use of orphan drugs, and drug exclusivity status received by orphan drugs. Moreover, US contributes substantially to the market which calls for strong R&D for development of orphan drugs.

Table Of Contents

1. Report Prologue

2. Executive Summary

3. Market Introduction

3.1 Definition

3.2 Scope Of The Study

3.3 Assumptions & Limitations

3.3.1 Assumptions

3.3.2 Limitations

3.4 Market Structure

4. Research Methodology

4.1 Research Process

4.2 Primary Research

4.3 Secondary Research

4.4 Market Size Estimation

4.5 Forecast Model

TOC Continued…

About US:

Market Research Future (MRFR), enable customers to unravel the complexity of various industries through Cooked Research Report (CRR), Half-Cooked Research Reports (HCRR), Raw Research Reports (3R), Continuous-Feed Research (CFR), and Market Research & Consulting Services.

Contact Us:

Market Research Future

Office No. 528, Amanora Chambers

Magarpatta Road, Hadapsar,

Pune - 411028

Maharashtra, India

Phone: +1 646 845 9312


Keywords: Orphan Drugs Market

By: Sumit Choudhari

Article Directory:

Copy and Paste Link Code:

Read other Articles from Sumit Choudhari: More »

Article ID 1080338 (Views 319)

Announcement from Our Sponsor

Cancer Drugs like Lenvima (generic version Lenvatinib), Imbruvica (generic version Ibrutinib) now have generic versions at tremendous savings. Brain boosting drugs like Provigil (generic version Modafinil) and Nuvigil (generic version Armodafinil) are also popular.

Sponsor Listing Canadian Pharmacy